Issue 2 (188), article 3

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DOI:https://doi.org/10.15407/kvt188.02.049

Kibern. vyčisl. teh., 2017, Issue 2 (188), pp.

Aralova N.I., senior researcher of department of optimization of controlled processes
e-mail: aralova@ukr.net
Institute of cybernetics of National Academy of Science of Ukraine,
Acad. Glushkov ave., 40, Kiev, 03680 GSP, Ukraine

RESERCH THE ROLE OF HYPOXIA, HYPERCAPHNIA AND HYPOMETABOLISM IN THE REGULATION OF THE RESPIRATORY SYSTEM IN THEIR INTERNAL AND EXTERNAL DISTURBANCES BASED ON THE MATHEMATICAL MODEL

Introduction. Under conditions of the physical exertion and human presence on the altitude, the oxygen deficiency in tissues occurs. For a theoretical study of the role of various mechanisms in the regulation of the respiratory system, the use of the mathematical model for the transport of respiratory gases in the body was proposed.

Purpose. Researches of the role of hypoxia, hypercapnia and hypometabolism in external and internal disturbances, based on the mathematical model of the respiratory system.

Results. On the mathematical model of respiratory gas transport in the dynamics of the respiratory cycle, as control parameters, pulmonary ventilation, minute blood volume and local blood flow, as well as self-regulation mechanisms — respiratory muscles, cardiac muscle and smooth muscle vessels — were used. It resolved the conflict situation that arises between the managers and the executive tissues in the fight for oxygen. An analysis of the results of numerical experiments in simulating hypoxia and hypoxic hypoxia and their comparison with experimental data was made.

Conclusion. The proposed approach can be useful in assessing the role of hypoxia, hypercapnia and hypometabolism in the disturbances of the internal and external environment in the process of human vital activity under extreme conditions and leads to the formulation of new tasks in the physiology of sports, work and leisure.

Keywords: Mathematical model of respiratory gas transport, load hypoxia, hypoxic hypoxia, regulation of the respiratory system, disturbing effects, oxygen deficiency.

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Recieved 29.03.2017